A synthetic 16-amino-acid peptide, unusual for being encoded within mitochondrial DNA rather than the nucleus. Supplied as a single-lot reference material.
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10 mg / vial · $3.36 / mg
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Every batch is identified by a lot number, and its third-party certificate is listed here by lot. Measured values are shown only when they are real and independently verifiable.
Third-party testing in progress
We are currently having this product independently tested by a third-party laboratory. Its certificate of analysis will be published here as soon as the results are available — please check back soon. For laboratory research use only.
MOTS-c is a synthetic research peptide of sixteen amino acids. It belongs in the mitochondrial and cellular-metabolism research collection, and it is unusual for being encoded within mitochondrial DNA rather than the cell nucleus.
Vestrand offers this as one batch at a time, prepared for outside verification, with each lot's certificate made available on its verification page once the analysis is signed off.
The name is the detail worth a second look. It is not named after any effect someone hoped for, but after where it comes from: a short stretch of mitochondrial DNA. The name records the peptide's origin and nothing else.
For laboratory research use only. Not for human or veterinary use.
MOTS-c is a 16-residue mitochondrial-derived peptide, encoded within mitochondrial rather than nuclear DNA. It is catalogued in mitochondrial and cellular-metabolism research; its name records its genomic origin, not a function.
Independent peer-reviewed literature that references MOTS-c.
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
Lee C et al.
Cell Metab2015
View source for The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance (opens in a new tab)MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism
Lee C et al.
Free Radic Biol Med2016
View source for MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism (opens in a new tab)The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress
Kim KH et al.
Cell Metab2018
View source for The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress (opens in a new tab)Mitochondrial-Encoded Peptide MOTS-c, Diabetes, and Aging-Related Diseases
Kong BS et al.
Diabetes Metab J2023
View source for Mitochondrial-Encoded Peptide MOTS-c, Diabetes, and Aging-Related Diseases (opens in a new tab)MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation
Zheng Y et al.
Front Endocrinol (Lausanne)2023
View source for MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation (opens in a new tab)Citations are provided for educational and scientific reference only. They describe independent published research and are not product claims — they do not represent the performance, purity, or intended use of any material offered for sale.
General handling guidance for laboratory research materials — always defer to the product label and the lot certificate of analysis.
Research use only
For laboratory research use only. Not for human or veterinary use.
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